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Article

MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5' region.

The EMBO journal - 18 Aug 2004

Mallory Allison C, Reinhart Brenda J, Jones-Rhoades Matthew W, Tang Guiliang, Zamore Phillip D, Barton M Kathryn, Bartel David P

Abstract excerpt

MicroRNAs (miRNAs) are approximately 22-nucleotide noncoding RNAs that can regulate gene expression by directing mRNA degradation or inhibiting productive translation. Dominant mutations in PHABULOSA (PHB) and PHAVOLUTA (PHV) map to a miR165/166 complementary site and impair miRNA-guided cleavage of these mRNAs in vitro. Here, we confirm that disrupted miRNA pairing, not changes in PHB protein sequence, causes...

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Identifiers

PMID: 15282547
DOI: 10.1038/sj.emboj.7600340
PMCID: PMC514513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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