Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spatially restricted microRNA directs leaf polarity through ARGONAUTE1.

Nature - 4 Mar 2004

Kidner Catherine A, Martienssen Robert A

Abstract excerpt

Gene regulation by RNA interference requires the functions of the PAZ domain protein Argonaute. In plants, mutations in ARGONAUTE1 (AGO1) are associated with distinctive developmental defects that suggest a role for microRNA (miRNA) in organ polarity. Potential targets of miRNA regulation are the homeodomain/leucine zipper genes PHABULOSA (PHB) and PHAVOLUTA (PHV). These genes are expressed in a polar fashion in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Argonaute Proteins
Share to Body Patterning
Share to Genes, Plant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Meristem

Share to MicroRNAs

Share to Plant Leaves

Share to RNA, Plant

Source

Identifiers

PMID: 14999284
DOI: 10.1038/nature02366

Genes

AGO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spatially restricted microRNA directs leaf polarity through ARGONAUTE1.PMID 14999284Read ↗

microRNA-mediated repression of rolled leaf1 specifies maize leaf polarity.Semantic proximity Read ↗

Class III HD-Zip gene regulation, the golden fleece of ARGONAUTE activity?Semantic proximity Read ↗

The role of ARGONAUTE1 (AGO1) in meristem formation and identity.Semantic proximity Read ↗

Plant ARGONAUTES.Semantic proximity Read ↗

The ARGONAUTE10 gene modulates shoot apical meristem maintenance and establishment of leaf polarity by repressing miR165/166 in Arabidopsis.Semantic proximity Read ↗

Specification of leaf polarity in Arabidopsis via the trans-acting siRNA pathway.Semantic proximity Read ↗

MicroRNA-directed cleavage of Nicotiana sylvestris PHAVOLUTA mRNA regulates the vascular cambium and structure of apical meristems.Semantic proximity Read ↗

Punctate vascular expression1 is a novel maize gene required for leaf pattern formation that functions downstream of the trans-acting small interfering RNA pathway.Semantic proximity Read ↗

The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development.Semantic proximity Read ↗

MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5' region.Semantic proximity Read ↗

ragged seedling2 Encodes an ARGONAUTE7-like protein required for mediolateral expansion, but not dorsiventrality, of maize leaves.Semantic proximity Read ↗

SERRATE: a new player on the plant microRNA scene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.