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Article

Metastatic cancer DNA phenotype identified in normal tissues surrounding metastasizing prostate carcinomas.

Proceedings of the National Academy of Sciences of the United States of America - 3 Aug 2004

Malins Donald C, Gilman Naomi K, Green Virginia M, Wheeler Thomas M, Barker Edward A, Vinson Mark A, Sayeeduddin Mohammad, Hellström Karl Erik, Anderson Katie M

Abstract excerpt

Fourier transform-infrared statistical models have the proven ability to identify subtle structural changes in DNA at various stages of tumor development. Using these models, we show evidence for a metastatic cancer DNA phenotype in histologically normal prostate tissues surrounding metastasizing tumors. Strikingly, the DNA base and backbone structures of the metastatic phenotype are indistinguishable from those...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15280533
DOI: 10.1073/pnas.0404572101
PMCID: PMC509217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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