Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metastasizing and non-metastasizing tumors likely evolve from DNA phenotypes via independent pathways.

Cell cycle (Georgetown, Tex.) - 1 Oct 2004

Malins Donald C

Abstract excerpt

We have recently discovered, using statistical models of Fourier transform-infrared spectra, two distinct cancer DNA phenotypes in histologically normal tissues surrounding non-metastasizing primary tumors and tumors with evidence of distant metastases. Structural comparisons of the DNA from thes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Neoplasm
Share to Mice
Share to Models, Biological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Metastasis

Share to Neoplasms

Share to Phenotype

Source

Identifiers

PMID: 15467465
DOI: 10.4161/cc.3.10.1169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15467465-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Metastasizing and non-metastasizing tumors likely evolve from DNA phenotypes via independent pathways.PMID 15467465Read ↗

Metastatic cancer DNA phenotype identified in normal tissues surrounding metastasizing prostate carcinomas.Semantic proximity Read ↗

Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases.Semantic proximity Read ↗

Origins of lymphatic and distant metastases in human colorectal cancerSemantic proximity Read ↗

Divergent and convergent evolution in metastases suggest treatment strategies based on specific metastatic sitesSemantic proximity Read ↗

Origin of metastases: subspecies of cancers generated by intrinsic karyotypic variations.Semantic proximity Read ↗

Frequency Maps of FTIR Images for Phenotyping Molecular Heterogeneity of the Primary Tumor and Its Metastases.Semantic proximity Read ↗

Age and Generation-Based Model of Metastatic Cancer: From Micrometastases to MacrometastasesSemantic proximity Read ↗

Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.