Discussing the predictive, prognostic, and therapeutic value of germline DNA-repair gene mutations in metastatic prostate cancer patients.

doi:10.1080/15384047.2017.1345398

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Discussing the predictive, prognostic, and therapeutic value of germline DNA-repair gene mutations in metastatic prostate cancer patients.

Cancer biology & therapy - 3 Aug 2017

Hauke Ralph J, Sissung Tristan M, Figg William D

Abstract excerpt

Recent trends in cancer therapy have begun emphasizing the use of precision medicine, especially genetic tools, in the evaluation of malignancies and decision-making. Prostate cancer is a malignancy where the benefits and utility of screening and early treatment are still heavily controversial. A recent paper in the New England Journal of Medicine found that patients with metastatic prostate cancer presented...

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PMID: 28678600
DOI: 10.1080/15384047.2017.1345398
PMCID: PMC5653188

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