Article
A role for DNA polymerase delta in gene conversion and crossing over during meiosis in Saccharomyces cerevisiae.
Genetics - 1 Jul 2004
Maloisel Laurent, Bhargava Jaya, Roeder G Shirleen
Abstract excerpt
A screen for mutants of budding yeast defective in meiotic gene conversion identified a novel allele of the POL3 gene. POL3 encodes the catalytic subunit of DNA polymerase delta, an essential DNA polymerase involved in genomic DNA replication. The new allele, pol3-ct, specifies a protein missing the last four amino acids. pol3-ct shows little or no defect in DNA replication, but displays a reduction in the length...
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