Article
Network responses to DNA damaging agents.
DNA repair - 1 Jan 2000
Begley Thomas J, Samson Leona D
Abstract excerpt
Global transcriptional profiling and large scale phenotypic studies have shown that eukaryotic cells mount a robust and complex response to damage. Further, systems biology approaches have employed powerful analytical methods to integrate global data sets with regulatory sequences, protein-DNA and protein-protein interactions, which have led to the identification of large networked responses to damage. A number...
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