Article
Mechanistic understanding of cellular responses to genomic stress.
Environmental and molecular mutagenesis - 1 Jan 2020
Hanawalt Philip, Sweasy Joann
Abstract excerpt
Within the past half century we have learned of multiple pathways for repairing damaged DNA, based upon the intrinsic redundancy of information in its complementary double strands. Mechanistic details of these pathways have provided insights into environmental and endogenous threats to genomic stability. Studies on bacterial responses to ultraviolet light led to the discovery of excision repair, as well as the...
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