Article
Gene expression profiling of purified rat retinal ganglion cells.
Investigative ophthalmology & visual science - 1 Aug 2004
Farkas Ronald H, Qian Jiang, Goldberg Jeffrey L, Quigley Harry A, Zack Donald J
Abstract excerpt
PURPOSE: The phenotype of specialized cells arises, in part, from their characteristic gene expression patterns. Retinal ganglion cells (RGCs) are of wide interest in neuroscience and die in glaucoma and other optic neuropathies. In this study the genes expressed by RGCs were profiled by expressed sequence tag (EST) analysis. METHODS: ESTs were generated from a cDNA library constructed from RGCs isolated by...
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