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Article

Protein profiling of human nonpigmented ciliary epithelium cell secretome: the differentiation factors characterization for retinal ganglion cell line.

Journal of biomedicine & biotechnology - 1 Jan 2011

Yang Ming-Hui, Krishnamoorthy Raghu R, Jong Shiang-Bin, Chu Pei-Yu, Yang Yuan-Han, Chen Wen-Cheng, Chen Sharon Chia-Ju, Dibas Adnan, Yorio Thomas, Chung Tze-Wen, Tyan Yu-Chang

Abstract excerpt

The purpose of this paper was to characterize proteins secreted from the human nonpigmented ciliary epithelial (HNPE) cells, which have differentiated a rat retinal ganglion cell line, RGC-5. Undifferentiated RGC-5 cells have been shown to express several marker proteins characteristic of retinal ganglion cells. However, RGC-5 cells do not respond to N-methyl-D aspartate (NMDA), or glutamate. HNPE cells have been...

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Identifiers

PMID: 21860587
DOI: 10.1155/2011/901329
PMCID: PMC3157028

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