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Article

Dysbindin gene (DTNBP1) in major depressive disorder (MDD) patients: lack of association with clinical phenotypes.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Dec 2010

Kocabas Neslihan Aygun, Antonijevic Irina, Faghel Carole, Forray Carlos, Kasper Siegfried, Lecrubier Yves, Linotte Sylvie, Massat Isabelle, Montgomery Stuart, Noro Magali, Oswald Pierre, Snyder Lenore, Souery Daniel, Zohar Joseph, Mendlewicz Julien

Abstract excerpt

OBJECTIVES: Dystrobrevin binding protein 1 (Dysbindin) is a plausible candidate gene for major depressive disorders (MDD) due to its involvement in synaptic signaling, plasticity and localization in the brain. METHODS: Two intronic SNPs of DTNBP1; rs760761 (P1320) and rs2619522 (P1763) were analyzed in 206 patients with DSM-IV MDD to investigate the functional impact of genotypes on susceptibility for depression...

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Source

Identifiers

PMID: 20822372
DOI: 10.3109/15622975.2010.512089

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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