Article
Dysbindin gene (DTNBP1) in major depressive disorder (MDD) patients: lack of association with clinical phenotypes.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Dec 2010
Kocabas Neslihan Aygun, Antonijevic Irina, Faghel Carole, Forray Carlos, Kasper Siegfried, Lecrubier Yves, Linotte Sylvie, Massat Isabelle, Montgomery Stuart, Noro Magali, Oswald Pierre, Snyder Lenore, Souery Daniel, Zohar Joseph, Mendlewicz Julien
Abstract excerpt
OBJECTIVES: Dystrobrevin binding protein 1 (Dysbindin) is a plausible candidate gene for major depressive disorders (MDD) due to its involvement in synaptic signaling, plasticity and localization in the brain. METHODS: Two intronic SNPs of DTNBP1; rs760761 (P1320) and rs2619522 (P1763) were analy...
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