Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of relationship between CO2 reactivity and serotonin transporter gene regulatory region polymorphism in panic disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Aug 2004

Perna Giampaolo, di Bella Daniela, Favaron Elisa, Cucchi Michele, Liperi Laura, Bellodi Laura

Abstract excerpt

Changes in the function of the serotonergic system influence both panic phobic symptoms and carbon dioxide (CO2) reactivity in patients with panic disorder. Schmidt et al. [2000: J Abnorm Psychol 109(2):308-320] recently reported a predictive role of the genetic variants of the 5-HTTLPR on the fearful response to CO2 in healthy controls. We tested the hypothesis that the heterogeneity of CO2 reactivity in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Inhalation
Share to Carbon Dioxide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Transport Proteins

Share to Panic Disorder

Share to Regulatory Sequences, Nucleic Acid

Share to Respiration Disorders

Share to Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 15274038
DOI: 10.1002/ajmg.b.30035

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of relationship between CO2 reactivity and serotonin transporter gene regulatory region polymorphism in panic disorder.PMID 15274038Read ↗

Genetic moderation of CO2-induced fear by 5-HTTLPR genotype.Semantic proximity Read ↗

A genetic study of the acute anxious response to carbon dioxide stimulation in man.Semantic proximity Read ↗

Tryptophan hydroxylase and serotonin transporter gene polymorphism does not affect the diagnosis, clinical features and treatment outcome of panic disorder in the Korean population.Semantic proximity Read ↗

Evaluating gene x psychological risk factor effects in the pathogenesis of anxiety: a new model approach.Semantic proximity Read ↗

Association study of serotonin-2A receptor gene polymorphism and panic disorder in patients from Canada and Germany.Semantic proximity Read ↗

Effect of serotonin transporter genotype on carbon dioxide-induced fear-related behavior in mice.Semantic proximity Read ↗

Family history of panic disorder and hypersensitivity to CO2 in patients with panic disorder.Semantic proximity Read ↗

Anxiety responses to CO2 inhalation in subjects at high-risk for panic disorder.Semantic proximity Read ↗

The novel brain-specific tryptophan hydroxylase-2 gene in panic disorder.Semantic proximity Read ↗

Amiloride-sensitive cation channel 2 genotype affects the response to a carbon dioxide panic challenge.Semantic proximity Read ↗

Loudness dependence of auditory evoked potentials is not associated with polymorphisms or haplotypes in the serotonin transporter gene in a community-based sample of German healthy volunteers.Semantic proximity Read ↗

A long-term prospective evaluation of first-degree relatives of panic patients who underwent the 35% CO2 challenge.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.