Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New GABAA receptor alpha5 subunit gene polymorphism that may confound genotyping.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Aug 2004

Vaquero C, Baca-Garcia E, Diaz-Sastre C, Perez-Rodriguez M M, Navio Acosta M, Saiz-Ruiz J, de Leon J, Fernandez-Piqueras J

Abstract excerpt

We report the discovery of a new GABAA receptor alpha5 subunit gene polymorphism close to the polymorphism described by Glatt et al. (GT)5GCGTGC(GT)21. This new polymorphism is of great importance, because it means that non-denaturing acrylamide gels used to separate the different alleles of the polymorphism described by Glatt et al. cannot distinguish an allele with the sequence: (GT)4GCGTGC(GT)n from another...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dinucleotide Repeats
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Electrophoresis, Polyacrylamide Gel

Share to Polymorphism, Single-Stranded Conformational

Share to Protein Subunits

Share to Receptors, GABA-A

Source

Identifiers

PMID: 15274034
DOI: 10.1002/ajmg.b.30048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New GABAA receptor alpha5 subunit gene polymorphism that may confound genotyping.PMID 15274034Read ↗

Human γ-Aminobutyric Acid-Type A Receptor α5 Subunit Gene (GABRA5): Characterization and Structural Organization of the 5′ Flanking RegionSemantic proximity Read ↗

Dinucleotide repeat polymorphism at the GABAA receptor alpha 5 (GABRA5) locus at chromosome 15q11-q13.Semantic proximity Read ↗

The alpha5(H105R) mutation impairs alpha5 selective binding properties by altered positioning of the alpha5 subunit in GABAA receptors containing two distinct types of alpha subunits.Semantic proximity Read ↗

Identification of a naturally occurring Pro385-Ser385 substitution in the GABA(A) receptor alpha6 subunit gene in alcoholics and healthy volunteers.Semantic proximity Read ↗

Association between GABA-A receptor alpha 5 subunit gene locus and schizophrenia of a later age of onset.Semantic proximity Read ↗

Molecular characterization of new polymorphisms at the beta2, alpha1, gamma2 GABA(A) receptor subunit genes associated to a rat nonpreferring ethanol phenotype.Semantic proximity Read ↗

Linkage disequilibrium of HLA-A11 and A1 with one of the polymorphisms of the gamma-aminobutyric acid receptor type B.Semantic proximity Read ↗

Human GABA(B) receptor 1 gene: eight novel sequence variants.Semantic proximity Read ↗

Association of alpha subunit of GABAA receptor subtype gene polymorphisms with epilepsy susceptibility and drug resistance in north Indian population.Semantic proximity Read ↗

Gamma-aminobutyric acid (GABA) receptors GABRA4, GABRE, and GABRQ gene polymorphisms and risk for migraine.Semantic proximity Read ↗

The GABA type A receptor alpha5 subunit gene is associated with bipolar I disorder.Semantic proximity Read ↗

Five mutations in the GABA A alpha6 gene 5' flanking region are associated with a reduced basal and ethanol-induced alpha6 upregulation in mutated Sardinian alcohol non-preferring rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.