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Article

Elevated Plasma C-reactive protein in chronically distressed subjects who carry the A allele of the TNF-alpha -308 G/A polymorphism.

Psychosomatic medicine - 1 Jan 2000

Jeanmonod Pascal, von Känel Roland, Maly Friedrich E, Fischer Joachim E

Abstract excerpt

OBJECTIVE: Sustained psychological stress may result in a state operationalized as "vital exhaustion." Exhaustion predicted coronary artery disease (CAD) events whereby increased inflammatory activity might mediate this link. Moreover, there is an emerging importance of gene-environmental interactions in CAD. We investigated the effect of exhaustion severity on plasma levels of C-reactive protein (CRP) and...

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Source

Identifiers

PMID: 15272094
DOI: 10.1097/01.psy.0000130903.78444.7d

Genes

CRP
TNF
CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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