Article
Transcription of a lepidopteran cytochrome P450 promoter is modulated by multiple elements in its 5' UTR and repressed by 20-hydroxyecdysone.
Insect molecular biology - 1 Aug 2004
Petersen Brown R, Berenbaum M R, Schuler M A
Abstract excerpt
The biochemical response to the phytochemical xanthotoxin encountered in the diet of black swallowtail larvae is the induction of P450s capable of detoxifying this and other toxic furanocoumarins. As the xenobiotic response element to xanthotoxin (XRE-xan) is necessary but not sufficient for transcription of the CYP6B1v3 gene in Sf9 cells, sequences upstream of it, such as a putative EcRE, and downstream of it,...
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