Article
Black swallowtail (Papilio polyxenes) alleles encode cytochrome P450s that selectively metabolize linear furanocoumarins.
Archives of biochemistry and biophysics - 1 May 1994
Ma R, Cohen M B, Berenbaum M R, Schuler M A
Abstract excerpt
Cytochrome P450 monooxygenases are involved in metabolism of hostplant allelochemicals by larval Lepidoptera. Biochemical purification of the P450 polypeptide induced in Papilio polyxenes (black swallowtail) larvae in response to xanthotoxin, a linear furanocoumarin, has allowed us to clone cDNAs encoding two allelic variants of the CYP6B1 locus. Expression of these alleles in lepidopteran cell lines using...
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