Article
Expansion and contraction of rhesus macaque DRB regions by duplication and deletion.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1994
Slierendregt B L, Otting N, van Besouw N, Jonker M, Bontrop R E
Abstract excerpt
Previous sequence analysis of the rhesus macaque MHC (MhcMamu) class II DRB region has allowed the detection of at least 34 alleles belonging to different lineages. In this communication, 36 new Mamu-DRB alleles are reported. The gene content of the DRB region has been determined for several homozygous animals of consanguineous origin. As in other primates, the number of DRB genes present per haplotype is not...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Consensus Sequence
- DNA
- DNA Primers
- Gene Deletion
- Genes, MHC Class II
- Gorilla gorilla
- Haplotypes
- Humans
