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Article

Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation

13 Jul 2004

Abstract excerpt

Testicular germ cell tumours (TGCT) represent the most common malignancies in young males. Whereas in 1970s, the survival rate in patients with metastatic testicular tumours was only 5%, these days, 80% of the patients treated by modern chemotherapy will survive their disease. The drug that revolutionised the cure rate for patients with metastatic testicular tumours was cisdiamminedichloroplatinum (cisplatin,...

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PMID: 15266324
DOI: 10.1038/sj.bjc.6601919

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Source receipt: pubmed, retrieved 7 Sept 2026.

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