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Article

Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles

21 Aug 2007

Abstract excerpt

BACKGROUND: Testicular germ cell tumors (TGCTs) respond well to cisplatin-based chemotherapy and show a low incidence of acquired resistance compared to most somatic tumors. The reasons for these specific characteristics are not known in detail but seem to be multifactorial. We have studied gene expression profiles of testicular and colon cancer derived cell lines treated with cisplatin. The main goal of this...

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PMID: 17711579
DOI: 10.1186/1476-4598-6-53

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