Article
The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase).
European journal of biochemistry - 1 Aug 2004
Potluri Prasanth, Yadava Nagendra, Scheffler Immo E
Abstract excerpt
The ESSS protein is a recently identified subunit of mammalian mitochondrial complex I. It is a relatively small integral membrane protein (122 amino acids) found in the beta-subcomplex. Genomic sequence database searches reveal its localization to the X-chromosome in humans and mouse. The ESSS cDNA from Chinese hamster cells was cloned and shown to complement one complementation group of our previously described...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Cell Respiration
- Cricetinae
- Electron Transport Complex I
- Enzyme Stability
- Humans
- Molecular Sequence Data
- Mutation