An automated assay of the behavioral effects of cocaine injections in adult Drosophila.

Abstract excerpt

Introducing Drosophila models in neuropharmacological research helps to discover new mechanisms of drug action. In fruit flies, the pharmacobehavioral approach has been used to evaluate the effects of drugs of abuse including cocaine. Standard procedures of cocaine administration to flies employ drug vaporization whereas behavior is evaluated either by trained observers or by videotaping followed by analysis via...

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