Article
Arabidopsis thaliana XRN2 is required for primary cleavage in the pre-ribosomal RNA.
Nucleic acids research - 1 Jul 2010
Zakrzewska-Placzek Monika, Souret Frederic F, Sobczyk Grzegorz J, Green Pamela J, Kufel Joanna
Abstract excerpt
Three Rat1/Xrn2 homologues exist in Arabidopsis thaliana: nuclear AtXRN2 and AtXRN3, and cytoplasmic AtXRN4. The latter has a role in degrading 3' products of miRNA-mediated mRNA cleavage, whereas all three proteins act as endogenous post-transcriptional gene silencing suppressors. Here we show that, similar to yeast nuclear Rat1, AtXRN2 has a role in ribosomal RNA processing. The lack of AtXRN2, however, does...
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