Article
Arabidopsis thaliana LSM proteins function in mRNA splicing and degradation.
Nucleic acids research - 1 Jul 2013
Golisz Anna, Sikorski Pawel J, Kruszka Katarzyna, Kufel Joanna
Abstract excerpt
Sm-like (Lsm) proteins have been identified in all organisms and are related to RNA metabolism. Here, we report that Arabidopsis nuclear AtLSM8 protein, as well as AtLSM5, which localizes to both the cytoplasm and nucleus, function in pre-mRNA splicing, while AtLSM5 and the exclusively cytoplasmic AtLSM1 contribute to 5'-3' mRNA decay. In lsm8 and sad1/lsm5 mutants, U6 small nuclear RNA (snRNA) was reduced and...
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