Article
Antiretroviral efficacy and virological profile of a zidovudine/lamivudine/tenofovir disoproxil fumarate combination therapy in antiretroviral-naive patients.
Antiviral therapy - 1 Jan 2006
Masquelier Bernard, Neau Didier, Boucher Sébastien, Lavignolle-Aurillac Valérie, Schrive Marie-Hélène, Recordon-Pinson Patricia, Ragnaud Jean-Marie, Fleury Hervé
Abstract excerpt
OBJECTIVE: To study the antiviral efficacy and the mutations selected by a triple therapy with zidovudine (AZT), lamivudine (3TC) and tenofovir disoproxil fumarate (TDF). METHODS: Antiretroviral-naive patients received 300 mg AZT/150 mg 3TC twice a day plus 300 mg TDF once a day in an open pilot study. Follow-up was assessed at baseline therapy (MO) and at months 1, 3, 6, 9 and 12. Reverse transcriptase (RT)...
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