Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic Gene Expression After Systemic Delivery of Plasmid DNA as Determined by <i>In Vivo</i> Bioluminescence Imaging

31 Oct 2005

Abstract excerpt

Nonviral gene therapy approaches face the challenge of achieving stable gene expression in target organs and tissues. We used fluorescence microscopy and in vivo imaging after rapid, high-volume delivery of plasmid DNA (pDNA) encoding DsRed and luciferase as products of the same mRNA to detect localized gene expression in liver. Plasmids encoding the luciferase gene transcriptionally regulated by cellular and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA Interference and Gene Delivery
Share to Viral gastroenteritis research and epidemiology
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16259566
DOI: 10.1089/hum.2005.16.1325

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic Gene Expression After Systemic Delivery of Plasmid DNA as Determined by <i>In Vivo</i> Bioluminescence ImagingPMID 16259566Read ↗

Systemic gene therapy: biodistribution and long-term expression of a transgene in mice.Semantic proximity Read ↗

Efficient Gene Delivery and Targeted Expression to Hepatocytes <i>In Vivo</i> by Improved Lentiviral VectorsSemantic proximity Read ↗

Positron Emission Tomography Reporter Genes and Reporter Probes: Gene and Cell Therapy ApplicationsSemantic proximity Read ↗

In vitro and in vivo comparative study of chimeric liver-specific promotersSemantic proximity Read ↗

Noninvasive Imaging of the Transcriptional Activities of Human Telomerase Promoter Fragments in MiceSemantic proximity Read ↗

Long-Term and Therapeutic-Level Hepatic Gene Expression of Human Factor IX after Naked Plasmid Transfer in VivoSemantic proximity Read ↗

Lipid nanoparticle technology for therapeutic gene regulation in the liverSemantic proximity Read ↗

Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genesSemantic proximity Read ↗

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearanceSemantic proximity Read ↗

High-Level Factor VIII Gene Expression <i>In Vivo</i> Achieved by Nonviral Liver-Specific Gene Therapy VectorsSemantic proximity Read ↗

Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene TransferSemantic proximity Read ↗

Swine reporter model for preclinical evaluation and characterization of gene delivery vectorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.