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Article

The Tumor Microenvironment Controls Primary Effusion Lymphoma Growth<b><i>in Vivo</i></b>

15 Jul 2004

Abstract excerpt

Certain lymphomas in AIDS patients, such as primary effusion lymphoma (PEL), are closely associated with the lymphotropic gamma herpes virus Kaposi's sarcoma-associated herpes virus (KSHV), also called human herpesvirus 8. The virus is thought to be essential for tumorigenesis, yet systems to investigate PEL in vivo are rare. Here we describe PEL tumorigenesis in a new xenograft model. Embedded in Matrigel, PEL...

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PMID: 15256448
DOI: 10.1158/0008-5472.can-03-3835

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