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The Zebrafish Xenograft Platform—A Novel Tool for Modeling KSHV-Associated Diseases

20 Dec 2019

Abstract excerpt

Kaposi’s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes. KSHV infection is typically asymptomatic, but immunosuppression can predispose KSHV-infected individuals to primary effusion lymphoma (PEL); a malignancy driven by aberrant proliferation of latently infected B lymphocytes, and supported by...

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PMID: 31861850
DOI: 10.3390/v12010012

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