Article
Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs.
American journal of respiratory cell and molecular biology - 1 Nov 2004
Bonniaud Philippe, Martin Gail, Margetts Peter J, Ask Kjetil, Robertson Jennifer, Gauldie Jack, Kolb Martin
Abstract excerpt
The individual susceptibility to pulmonary fibrosis (PF) remains a mystery, suggesting a role for genetic predisposition. The pathogenesis of PF involves a multitude of factors mediating crosstalk between various tissue components. Some factors, such as transforming growth factor beta, are recognized as key elements in the process, whereas the role of others, such as connective tissue growth factor (CTGF), is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
