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Article

Development of pancreatic islets in pancreatic polypeptide-overexpressing mice.

International journal of molecular medicine - 1 Aug 2004

Yuzuriha Hideki, Inui Akio, Asakawa Akihiro, Ueno Naohiko, Sakamaki Ruka, Shinfuku Naotaka, Kasuga Masato, Fujimiya Mineko

Abstract excerpt

Recently we produced pancreatic polypeptide transgenic (PPTG) mice and found that PP was overexpressed in pancreatic islets. The present study examines development of four islet hormones in PPTG mice at embryonic days (ED) 15, 17, and 19, and in adult animals. Adult PPTG mice showed massive aggregation of PP-positive cells and glucagon-positive cells seen at the central area of the islets. Confocal laser...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15254766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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