Article
Zebrafish as a model for studying functional pancreatic β cells development and regeneration
1 Aug 2018
Abstract excerpt
Pancreatic β cells produce insulin and play a central role in glucose homeostasis. The regenerative capacity of mammalian β cells is limited, so that loss and dysfunction of β cells causes diabetes. Zebrafish have a pancreas which is functionally and morphologically conserved with human pancreas. Zebrafish have high regenerative capacity of islets. In the present review, development of zebrafish pancreas was...
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