Article
The Plasmodium falciparum Vps4 homolog mediates multivesicular body formation.
Journal of cell science - 1 Aug 2004
Yang Mei, Coppens Isabelle, Wormsley Steve, Baevova Pavlina, Hoppe Heinrich C, Joiner Keith A
Abstract excerpt
Members of the apicomplexan family of parasites contain morphologically unique secretory organelles termed rhoptries that are essential for host cell invasion. Rhoptries contain internal membranes, and thus resemble multivesicular bodies. To determine whether multivesicular body endosomal intermediates are formed in Apicomplexa, we used the Plasmodium falciparum homolog of the class E gene, Vps4, as a probe....
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