Article

An ER-resident lipid scramblase is crucial for biogenesis and function of apicomplexan parasite secretory organelles

2024-11-15

Abstract excerpt

Apicomplexan parasites, including Plasmodium falciparum and Toxoplasma gondii , contain specialized secretory organelles such as micronemes, rhoptries, and dense granules, which are essential for parasite motility, host cell invasion, development, and egress. DedA superfamily proteins are implicated in lipid mobilization, which is a key requirement for organelle biogenesis. Herein, we identified and investigated...

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Literature Corpus work: 6a0638bf-74dc-53f5-9ac8-3b4cccb6ea92
DOI: 10.1101/2024.11.14.623710

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