Article
Dual transcripts of BCR-ABL & different polymorphisms in chronic myeloid leukaemia patients.
The Indian journal of medical research - 1 May 2016
Nandagopalan S Rajashree, Kuila Nivedita, Biswas Sutapa, Pattnayak Naresh Chandra, Biswas Gyanashyam, Chakraborty Soumen
Abstract excerpt
BACKGROUND & OBJECTIVES: Chronic myeloid leukaemia is (CML) characterized by the presence of a hallmark chromosomal translocation, the Philadelphia chromosome. Although there are many reports available regarding the different variants of BCR-ABL in CML, we studied the co-expression of e13a2 and e14a2 transcripts and a few polymorphisms in CML patients. METHODS: Molecular genetics approach was adapted to screen...
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