Article
[Polymorphisms in the breakpoint cluster region of bcr gene].
Zhongguo shi yan xue ye xue za zhi - 1 Jun 2008
Tian Hong, Zhou Shu-Yun
Abstract excerpt
This study was aimed to explore the single nucleotide polymorphism (SNPs) of breakpoint cluster region of bcr gene in Chinese people and the relationship between SNPs and chronic myelogenous leukemia (CML). A 3.12 kb region spanning from exon 13 to exon 15 in the bcr region were screened by DNA pooling and denaturing high performance liquid chromatography (dHPLC), and the results were verified by sequencing. The...
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