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Article

Multimerization of poly(rC) binding protein 2 is required for translation initiation mediated by a viral IRES.

RNA (New York, N.Y.) - 1 Aug 2004

Bedard Kristin M, Walter Brandon L, Semler Bert L

Abstract excerpt

The cellular protein, poly(rC) binding protein 2 (PCBP2), is known to function in picornavirus cap-independent translation. We have further examined the RNA binding properties and protein-protein interactions of PCBP2 necessary for translation. We have studied its putative multimerization properties utilizing the yeast two-hybrid assay and in vitro biochemical methods, including glutathione S-transferase (GST)...

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Source

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Identifiers

PMID: 15247434
DOI: 10.1261/rna.7070304
PMCID: PMC1370616

Genes

PCBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multimerization of poly(rC) binding protein 2 is required for translation initiation mediated by a viral IRES.PMID 15247434Read ↗

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