Article
Looking for immunological risk genotypes.
Annals of the New York Academy of Sciences - 1 Jun 2004
Caruso Calogero, Aquino Alessandra, Candore Giuseppina, Scola Letizia, Colonna-Romano Giuseppina, Lio Domenico
Abstract excerpt
Several functional markers of the immune system may be used either as markers of successful aging or conversely as markers of unsuccessful aging. Particularly, a combination of high CD8 and low CD4 and poor T cell proliferation has been associated with a higher two-year mortality in very old subjects. Therefore, genetic determinants of longevity should reside in those polymorphisms for the immune system genes...
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