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Article

Adult-onset Alopecia areata is a complex polygenic trait in the C3H/HeJ mouse model.

The Journal of investigative dermatology - 1 Aug 2004

Sundberg John P, Silva Kathleen A, Li Renhua, Cox Gregory A, King Lloyd E

Abstract excerpt

Alopecia areata (AA) is an autoimmune disease that targets actively growing (anagen) hair follicles in humans and other mammals. C3H/HeJ, but not C57BL/6J, mice spontaneously develop an adult-onset form of AA. A segregating population of C3HB6F2 female mice (n=1096), generated from crossing these two strains, was used for genome-wide linkage analysis to identify AA genetic susceptibility. Previous analysis...

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PMID: 15245428
DOI: 10.1111/j.0022-202X.2004.23222.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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