Article
A patient with both bullous pemphigoid and epidermolysis bullosa acquisita: an example of intermolecular epitope spreading.
Journal of the American Academy of Dermatology - 1 Jul 2004
Fairley Janet A, Woodley David T, Chen Mei, Giudice George J, Lin Mong-Shang
Abstract excerpt
Bullous pemphigoid (BP) and epidermolysis bullosa acquisita are distinct autoimmune blistering disorders. BP is characterized by autoantibodies directed against the NC16A domain of collagen XVII, whereas patients with epidermolysis bullosa acquisita have autoantibodies against the NC1 domain of type VII collagen. We followed up a patient with BP for 9 years. During that time his clinical disease took on several...
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