Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Severity and phenotype of bullous pemphigoid relate to autoantibody profile against the NH2- and COOH-terminal regions of the BP180 ectodomain.

The Journal of investigative dermatology - 1 Nov 2002

Hofmann SilkeC, Thoma-Uszynski Sybille, Hunziker Thomas, Bernard Philippe, Koebnick Corinna, Stauber Angelika, Schuler Gerold, Borradori Luca, Hertl Michael

Abstract excerpt

Bullous pemphigoid, the most common autoimmune subepidermal bullous disorder, is associated with autoantibodies targeting antigenic sites clustered within the extracellular domain of BP180. To investigate epitope and subclass specificity of autoantibodies in bullous pemphigoid, we developed an en...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantigens
Share to Collagen Type XVII

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin A

Share to Immunoglobulin E

Share to Immunoglobulin G

Share to Mucous Membrane

Share to Non-Fibrillar Collagens

Share to Pemphigoid, Bullous

Source

Identifiers

PMID: 12445194
DOI: 10.1046/j.1523-1747.2002.19529.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12445194-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Severity and phenotype of bullous pemphigoid relate to autoantibody profile against the NH2- and COOH-terminal regions of the BP180 ectodomain.PMID 12445194Read ↗

Autoreactive T and B cells from bullous pemphigoid (BP) patients recognize epitopes clustered in distinct regions of BP180 and BP230.Semantic proximity Read ↗

Characterization of the anti-BP180 autoantibody reactivity profile and epitope mapping in bullous pemphigoid patients.Semantic proximity Read ↗

Clinical and immunological profiles of anti-BP230-type bullous pemphigoid: Restriction of epitopes to the C-terminal domain of BP230, shown by novel ELISAs of BP230-domain specific recombinant proteinsSemantic proximity Read ↗

Bullous pemphigoid antigen II (BP180) and its soluble extracellular domains are major autoantigens in mucous membrane pemphigoid: the pathogenic relevance to HLA class II alleles and disease severity.Semantic proximity Read ↗

Epitopes targeted by bullous pemphigoid T lymphocytes and autoantibodies map to the same sites on the bullous pemphigoid 180 ectodomain.Semantic proximity Read ↗

The role of antibody class and target on subepidermal blistering disease phenotype and management.Semantic proximity Read ↗

Cloning and Primary Structural Analysis of the Bullous Pemphigoid Autoantigen BP180Semantic proximity Read ↗

BP180 as the common autoantigen in blistering diseases with different clinical phenotypes.Semantic proximity Read ↗

IgE autoantibodies and their association with the disease activity and phenotype in bullous pemphigoid: a systematic review.Semantic proximity Read ↗

Detection of IgE autoantibodies to BP180 and BP230 and their relationship to clinical features in bullous pemphigoid.Semantic proximity Read ↗

BP180/Collagen XVII: A Molecular ViewSemantic proximity Read ↗

Correlation of Serum Levels of IgE Autoantibodies Against BP180 With Bullous Pemphigoid Disease Activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.