Article
Glucocorticoid and mineralocorticoid receptors and associated diseases.
Essays in biochemistry - 1 Jan 2004
Kino Tomoshige, Chrousos George P
Abstract excerpt
Adrenal corticosteroids, i.e. glucocorticoids and mineralocorticoids, play important physiological roles in humans. Their actions are mediated by intracellular receptor molecules, the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), which function as hormone-dependent transcription factors. Ligand-activated receptors modulate the transcription rates of responsive genes by interacting with...
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