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Article

Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide.

The EMBO journal - 21 Jul 2004

Garcia Patrick L, Liu Yilun, Jiricny Josef, West Stephen C, Janscak Pavel

Abstract excerpt

Proteins belonging to the highly conserved RecQ helicase family are essential for the maintenance of genomic stability. Here, we describe the biochemical properties of the human RECQ5beta protein. Like BLM and WRN, RECQ5beta is an ATP-dependent 3'-5' DNA helicase that can promote migration of Holliday junctions. However, RECQ5beta required the single-stranded DNA-binding protein RPA in order to mediate the...

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Share to Adenosine Triphosphatases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 15241474
DOI: 10.1038/sj.emboj.7600301
PMCID: PMC514958

Genes

BLM
WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide.PMID 15241474Read ↗

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