Article
Imaging correlates of molecular signatures in oligodendrogliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2004
Megyesi Joseph F, Kachur Edward, Lee Donald H, Zlatescu Magdalena C, Betensky Rebecca A, Forsyth Peter A, Okada Yoshifumi, Sasaki Hikaru, Mizoguchi Masahiro, Louis David N, Cairncross J Gregory
Abstract excerpt
Molecular subsets of oligodendroglioma behave in biologically distinct ways. Their locations in the brain, rates of growth, and responses to therapy differ with their genotypes. Retrospectively, we inquired whether allelic loss of chromosomal arms 1p and 19q, an early molecular event and favorable prognostic marker in oligodendrogliomas, were reflected in their appearance on magnetic resonance imaging. Loss of 1p...
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