Article
Molecular imaging of gliomas.
Clinical neuropathology - 1 Jan 2000
Metz Marie-Christin, Wiestler Benedikt
Abstract excerpt
Molecular characterization has become a key diagnostic tool for the classification and grading of primary brain tumors. Molecular markers, such as isocitrate dehydrogenase (IDH) mutation status, 1p/19q codeletion, methylation of the O(6)-methylguanine-DNA methyltransferase (MGMT) promoter, or CDKN2A/B homozygous deletion discriminate different tumor entities and grades, and play a crucial role for treatment...
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