Microsatellite instability as indicator of MSH2 gene mutation in patients with upper urinary tract transitional cell carcinoma

Abstract excerpt

Upper urinary tract transitional cell carcinoma (UUTTCC) accounts for 5% of all urothelial carcinomas.1 Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant syndrome predisposing to colorectal cancer that accounts for about 5% of all colorectal cancers.2 It is revealed by colorectal cancer (63%) or extracolonic cancers, most often of the endometrium (9%) or ovary, but sometimes of the upper...

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