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Article

Progress in DNA‐based heterologous prime‐boost immunization strategies for malaria

5 May 2004

Abstract excerpt

An effective vaccine against malaria is urgently required to relieve the immense human suffering and mortality caused by this parasite. A successful subunit vaccine against the liver stage of malaria will require the induction of high levels of protective T cells. Despite success in small animal models, DNA vaccines fail to induce strong cellular immune responses in humans. However, DNA vaccines can induce a...

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PMID: 15233731
DOI: 10.1111/j.0105-2896.2004.00138.x

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