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Evidence for a Novel Gene Expression Program in Peripheral Blood Mononuclear Cells fromMycobacterium aviumsubsp.paratuberculosis-Infected Cattle

24 Oct 2003

Abstract excerpt

A bovine-specific cDNA microarray system was used to compare gene expression profiles of peripheral blood mononuclear cells (PBMCs) from control uninfected (n = 4) and Johne's disease-positive (n = 6) Holstein cows. Microarray experiments were designed so that for each animal, a direct comparison was made between PBMCs stimulated in vitro with Mycobacterium avium subsp. paratuberculosis and PBMCs stimulated with...

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PMID: 14573671
DOI: 10.1128/iai.71.11.6487-6498.2003

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