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Gene Expression Profiling of Peripheral Blood Mononuclear Cells from Cattle Infected with<i>Mycobacterium paratuberculosis</i>

12 Sept 2002

Abstract excerpt

A bovine-specific cDNA microarray system containing 721 unique leukocyte expressed sequence tags (ESTs) and amplicons representing known genes was used to compare gene expression profiles of peripheral blood mononuclear cells (PBMCs) from clinical and subclinical Johne's disease-positive Holstein cows (n = 2 per group). Stimulation of PBMCs from clinically infected cows with Mycobacterium paratuberculosis tended...

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PMID: 12228275
DOI: 10.1128/iai.70.10.5494-5502.2002

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