Article
Influence of mutations affecting gonadotropin production or responsiveness on expression of inhibin subunit mRNA and protein in the mouse ovary.
Reproduction (Cambridge, England) - 1 Jul 2004
Hirst Rachel C, Abel Margaret H, Wilkins Vivienne, Simpson Christine, Knight Phil G, Zhang Fu-Ping, Huhtaniemi Ilpo, Kumar T Rajendra, Charlton Harry M
Abstract excerpt
Measurement of inhibins A and B in the serum of normal cyclic rodents has implicated FSH in the regulation of these peptides within the ovary. To extend these observations we have used a panel of mutant mice carrying mutations which affect either the production of, or the ability to respond to, FSH and LH. As a consequence, the females are infertile and show different degrees of follicular development. The aim of...
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