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Article

Infectious cycle analysis of a Borrelia burgdorferi mutant defective in transport of chitobiose, a tick cuticle component.

Vector borne and zoonotic diseases (Larchmont, N.Y.) - 1 Jan 2004

Tilly Kit, Grimm Dorothee, Bueschel Dawn M, Krum Jonathan G, Rosa Patricia

Abstract excerpt

Chitobiose is the dimer subunit of chitin, a component of tick cuticle and peritrophic matrix, which is not found in mammals. The Borrelia burgdorferi chbC gene is required for the use of chitobiose as a source of the essential nutrient N-acetyl glucosamine during growth in vitro. In order to investigate the role of chitobiose transport in the infectious cycle, we constructed isogenic chbC mutant and wild-type...

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PMID: 15228817
DOI: 10.1089/1530366041210738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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