Article
Possible linkage between specific histological structures and aberrant reactivation of the Wnt pathway in adamantinomatous craniopharyngioma.
The Journal of pathology - 1 Jul 2004
Kato Keisuke, Nakatani Yukio, Kanno Hiroshi, Inayama Yoshiyuki, Ijiri Rieko, Nagahara Noriyuki, Miyake Tetsumi, Tanaka Mio, Ito Yumi, Aida Noriko, Tachibana Katsuhiko, Sekido Ken-ichi, Tanaka Yukichi
Abstract excerpt
This study concerns the significance of nuclear/cytoplasmic expression of beta-catenin and mutation of the beta-catenin gene in craniopharyngiomas. Fourteen adamantinomatous type and one squamous papillary type craniopharyngiomas were studied. Histologically, 13 of 14 adamantinomatous type craniopharyngiomas showed typical features, ie mixtures of 'palisading cells', 'stellate cells', and 'ghost cells'. In...
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